9CCD

DeltaNhp10 INO80 bound to S.c 0/40 nucleosome, INO80 core module

This is a non-PDB format compatible entry.

Summary for 9CCD

• Entry DOI: 10.2210/pdb9ccd/pdb
• EMDB information: 45441
• Descriptor: Chromatin-remodeling ATPase INO80, Actin-related protein 5, Chromatin-remodeling complex subunit IES6, ... (7 entities in total)
• Functional Keywords: chromatin remodeler, nucleosome, dna binding protein
• Biological source: Saccharomyces cerevisiae (brewer's yeast); More
• Total number of polymer chains: 10
• Total formula weight: 619884.22

Authors

Wu, H.,Kaur, U.,Narlikar, G.J.,Cheng, Y.F. (deposition date: 2024-06-21, release date: 2025-07-16)

• Primary citation: Kaur, U.,Wu, H.,Cheng, Y.,Narlikar, G.J.; Autoinhibition imposed by a large conformational switch of INO80 regulates nucleosome positioning; Science, 2025; DOI: 10.1126/science.adr3831

Experimental method

ELECTRON MICROSCOPY (3.01 Å)