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9CC5

De novo design of high-affinity protein binders to bio active peptide Amylin

Summary for 9CC5
Entry DOI10.2210/pdb9cc5/pdb
DescriptorAmylin-NHO-22 Binder, Islet amyloid polypeptide (3 entities in total)
Functional Keywordsprotein design, diffusion, deep learning, de novo protein, binders, idp, idr, amyloid, phase separation
Biological sourcesynthetic construct
More
Total number of polymer chains2
Total formula weight19067.38
Authors
Bera, A.K.,Liu, C.,Kang, A.,Baker, D. (deposition date: 2024-06-20, release date: 2025-05-14)
Primary citationLiu, C.,Bera, A.K.,Baker, D.
Diffusing protein binders to intrinsically disordered proteins
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.87 Å)
Structure validation

237735

數據於2025-06-18公開中

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