9CBZ

Cryo-EM structure of mouse TRPML1 channel Y404W at 2.86 Angstrom resolution

Summary for 9CBZ

• Entry DOI: 10.2210/pdb9cbz/pdb
• EMDB information: 45429
• Descriptor: Mucolipin-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• Functional Keywords: trpml1 channel, membrane protein
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 4
• Total formula weight: 264084.23

Authors

Gan, N.,Jiang, Y. (deposition date: 2024-06-20, release date: 2024-10-09)

• Primary citation: Gan, N.,Han, Y.,Zeng, W.,Jiang, Y.; TRPML1 gating modulation by allosteric mutations and lipids.; Biorxiv, 2024; PubMed: 39005349; DOI: 10.1101/2024.07.04.602033

Experimental method

ELECTRON MICROSCOPY (2.86 Å)