9C9O

M. tuberculosis PKS13 acyltransferase (AT) domain in complex with SuFEx inhibitor CMX410 - reaction product

This is a non-PDB format compatible entry.

Summary for 9C9O

• Entry DOI: 10.2210/pdb9c9o/pdb
• Related: 9C0P 9C1C 9C1D 9C1V 9C2R
• Related PRD ID: PRD_900003
• Descriptor: Polyketide synthase Pks13, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, SULFATE ION, ... (7 entities in total)
• Functional Keywords: polyketide synthase, acyltransferase domain, inhibitor, mycobacteria, structural genomics, tb structural genomics consortium, tbsgc, transferase
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); More
• Total number of polymer chains: 3
• Total formula weight: 170353.64

Authors

Krieger, I.V.,Tang, S.,Sacchetini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2024-06-14, release date: 2025-05-07)

• Primary citation: Krieger, I.V.,Sacchetini, J.C.; A SuFEx-based TB clinical candidate irreversibly inhibits Pks13; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.02 Å)