9C82

Structure of human ULK1C:PI3KC3-C1 supercomplex

This is a non-PDB format compatible entry.

Replaces:  8SRQ

Summary for 9C82

• Entry DOI: 10.2210/pdb9c82/pdb
• Related: 8SOI 8SQZ 8SRM
• EMDB information: 45297
• Descriptor: Phosphoinositide 3-kinase regulatory subunit 4, Phosphatidylinositol 3-kinase catalytic subunit type 3, Beclin 1-associated autophagy-related key regulator, ... (5 entities in total)
• Functional Keywords: autophagy, protein kinase, lipid kinase, supercomplex, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 435640.13

Authors

Chen, M.,Hurley, J.H. (deposition date: 2024-06-11, release date: 2024-07-03)

• Primary citation: Chen, M.,Ren, X.,Cook, A.,Hurley, J.H.; Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex; bioRxiv, 2023; DOI: 10.1101/2023.06.01.543278

Experimental method

ELECTRON MICROSCOPY (6.84 Å)