9C76

LRRK2 Roc domain RP (Ras-pocket) complexed to Divarasib

This is a non-PDB format compatible entry.

Summary for 9C76

• Entry DOI: 10.2210/pdb9c76/pdb
• Descriptor: Leucine-rich repeat serine/threonine-protein kinase 2, GUANOSINE-5'-DIPHOSPHATE, BROMIDE ION, ... (8 entities in total)
• Functional Keywords: gtpase, complex, chemical biology, switch ii, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 45476.39

Authors

Zhu, L.Y.,Guiley, K.Z.,Shokat, K.M. (deposition date: 2024-06-10, release date: 2024-12-11, Last modification date: 2024-12-25)

• Primary citation: Zhu, L.Y.,Shokat, K.M.; LRRK2 Roc domain RP (Ras-pocket) complexed to Divarasib; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)