9C55
Crystal structure of human PTPN2 in complex with active site inhibitor
Summary for 9C55
Entry DOI | 10.2210/pdb9c55/pdb |
Related | 9C54 |
Descriptor | Tyrosine-protein phosphatase non-receptor type 2, 5-(3-{[1-(BENZYLSULFONYL)PIPERIDIN-4-YL]AMINO}PHENYL)-4-BROMO-3-(CARBOXYMETHOXY)THIOPHENE-2-CARBOXYLIC ACID (3 entities in total) |
Functional Keywords | phosphatase, apo, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 37325.13 |
Authors | Bester, S.M.,Linwood, R.,Wu, W.-I.,Mou, T.-C. (deposition date: 2024-06-05, release date: 2024-09-04) |
Primary citation | Bester, S.M.,Linwood, R.,Kataoka, R.,Wu, W.I.,Mou, T.C. Enhancing the apo protein tyrosine phosphatase non-receptor type 2 crystal soaking strategy through inhibitor-accessible binding sites. Acta Crystallogr.,Sect.F, 2024 Cited by PubMed: 39177701DOI: 10.1107/S2053230X24007866 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.36 Å) |
Structure validation
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