9C29

Hexadecamer of NL4-3 WT HIV-1 intasome

Summary for 9C29

• Entry DOI: 10.2210/pdb9c29/pdb
• EMDB information: 45151
• Descriptor: Integrase, DNA (5'-D(*AP*CP*TP*GP*CP*TP*AP*GP*AP*GP*AP*TP*TP*TP*TP*CP*CP*CP*G)-3'), DNA (5'-D(P*CP*GP*GP*GP*AP*AP*AP*AP*TP*CP*TP*CP*TP*AP*GP*CP*A)-3'), ... (4 entities in total)
• Functional Keywords: viral protein, protein complex, viral protein-dna complex, viral protein/dna
• Biological source: HIV-1 06TG.HT008; More
• Total number of polymer chains: 20
• Total formula weight: 538046.15

Authors

Lyumkis, D.,Jing, T.,Zhang, Z. (deposition date: 2024-05-30, release date: 2025-06-25)

• Primary citation: Jing, T.,Shan, Z.,Dinh, T.,Biswas, A.,Jang, S.,Greenwood, J.,Li, M.,Zhang, Z.,Gray, G.,Shin, H.J.,Zhou, B.,Passos, D.,Strutzenberg, T.S.,Aiyer, S.,Andrade, L.,Zhang, Y.,Li, Z.,Craigie, R.,Engelman, A.N.,Kvaratskhelia, M.,Lyumkis, D.; Oligomeric HIV-1 Integrase Structures Reveal Functional Plasticity for Intasome Assembly and RNA Binding; Biorxiv, 2025; DOI: 10.1101/2024.01.26.577436

Experimental method

ELECTRON MICROSCOPY (8 Å)