9C0B

E.coli GroEL + PBZ1587 inhibitor

This is a non-PDB format compatible entry.

Summary for 9C0B

• Entry DOI: 10.2210/pdb9c0b/pdb
• EMDB information: 45078
• Descriptor: 60 kDa chaperonin, N-(2-{4-[4-(aminomethyl)benzene-1-sulfonamido]phenyl}-1,3-benzoxazol-5-yl)-5-chlorothiophene-2-sulfonamide (2 entities in total)
• Functional Keywords: groel, inhibitor, chaperone
• Biological source: Escherichia coli
• Total number of polymer chains: 14
• Total formula weight: 807509.51

Authors

Watson, E.R.,Lander, G.C. (deposition date: 2024-05-25, release date: 2024-08-07)

• Primary citation: Godek, J.,Sivinski, J.,Watson, E.R.,Lebario, F.,Xu, W.,Stevens, M.,Zerio, C.J.,Ambrose, A.J.,Zhu, X.,Trindl, C.A.,Zhang, D.D.,Johnson, S.M.,Lander, G.C.,Chapman, E.; Bis-sulfonamido-2-phenylbenzoxazoles Validate the GroES/EL Chaperone System as a Viable Antibiotic Target.; J.Am.Chem.Soc., 2024; PubMed: 39041457; DOI: 10.1021/jacs.4c05057

Experimental method

ELECTRON MICROSCOPY (3.26 Å)