9BRF
Crystal Structure of Human G Protein-Coupled Receptor Kinase 5 in Complex with GRL004-21
This is a non-PDB format compatible entry.
Summary for 9BRF
| Entry DOI | 10.2210/pdb9brf/pdb |
| Descriptor | G protein-coupled receptor kinase 5, (3Z)-3-{[3,5-dimethyl-4-(2-oxo-2-phenylacetamido)-1H-pyrrol-2-yl]methylidene}-2-oxo-N-[(1R)-1-phenylethyl]-3,7-dihydro-2H-indole-5-carboxamide (3 entities in total) |
| Functional Keywords | g protein-coupled receptor, gpcr g protein-coupled receptor kinase, grk kinase, signaling protein-inhibitor complex, signaling protein/inhibitor |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 69464.32 |
| Authors | |
| Primary citation | Chen, Y.,Tesmer, J.J.G. Structural insights into a class of GRK5 inhibitors To Be Published, |
| Experimental method | X-RAY DIFFRACTION (2.84 Å) |
Structure validation
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