9BOW

X-ray structure of Thermus thermophilus serine hydroxymethyltransferase with PLP-L-Ser external aldimine and 5-formyltetrahydrofolate (folinic acid)

Summary for 9BOW

• Entry DOI: 10.2210/pdb9bow/pdb
• Descriptor: Serine hydroxymethyltransferase, SERINE, SULFATE ION, ... (7 entities in total)
• Functional Keywords: pyridoxal 5'-phosphate, plp, fold type 1, one carbon metabolism, transferase
• Biological source: Thermus thermophilus HB8; More
• Total number of polymer chains: 2
• Total formula weight: 89630.12

Authors

Drago, V.N.,Kovalevsky, A. (deposition date: 2024-05-06, release date: 2024-08-28)

• Primary citation: Drago, V.N.,Phillips, R.S.,Kovalevsky, A.; Universality of critical active site glutamate as an acid-base catalyst in serine hydroxymethyltransferase function.; Chem Sci, 15:12827-12844, 2024; PubMed: 39148791; DOI: 10.1039/d4sc03187c

Experimental method

X-RAY DIFFRACTION (1.8 Å)