9BOW

X-ray structure of Thermus thermophilus serine hydroxymethyltransferase with PLP-L-Ser external aldimine and 5-formyltetrahydrofolate (folinic acid)

9BOW の概要

• エントリーDOI: 10.2210/pdb9bow/pdb
• 分子名称: Serine hydroxymethyltransferase, SERINE, SULFATE ION, ... (7 entities in total)
• 機能のキーワード: pyridoxal 5'-phosphate, plp, fold type 1, one carbon metabolism, transferase
• 由来する生物種: Thermus thermophilus HB8; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 89630.12

構造登録者

Drago, V.N.,Kovalevsky, A. (登録日: 2024-05-06, 公開日: 2024-08-28)

• 主引用文献: Drago, V.N.,Phillips, R.S.,Kovalevsky, A.; Universality of critical active site glutamate as an acid-base catalyst in serine hydroxymethyltransferase function.; Chem Sci, 15:12827-12844, 2024; PubMed: 39148791; DOI: 10.1039/d4sc03187c

実験手法

X-RAY DIFFRACTION (1.8 Å)