9BLN

The structure of human Pdcd4 bound to the 40S-eIF4A-eIF3-eIF1 complex

This is a non-PDB format compatible entry.

Summary for 9BLN

• Entry DOI: 10.2210/pdb9bln/pdb
• Related: 9BKD
• EMDB information: 44671
• Descriptor: Eukaryotic translation initiation factor 3 subunit I, Small ribosomal subunit protein uS17, Small ribosomal subunit protein eS4, X isoform, ... (55 entities in total)
• Functional Keywords: pdcd4, eif4a, ribosome, 43s, translation, antitumor protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 50
• Total formula weight: 2040668.98

Authors

Brito Querido, J.,Sokabe, M.,Diaz-Lopez, I.,Gordiyenko, Y.,Zuber, P.,Yifei, D.,Albacete-Albacete, L.,Ramakrishnan, V.,S Fraser, C. (deposition date: 2024-04-30, release date: 2024-09-04)

• Primary citation: Brito Querido, J.,Sokabe, M.,Diaz-Lopez, I.,Gordiyenko, Y.,Zuber, P.,Du, Y.,Albacete-Albacete, L.,Ramakrishnan, V.,Fraser, C.S.; Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit.; Nat Commun, 15:6633-6633, 2024; PubMed: 39117603; DOI: 10.1038/s41467-024-50672-8

Experimental method

ELECTRON MICROSCOPY (3.9 Å)