9BHR

Crystal structure of the WDR domain of human DCAF1 in complex with OICR-40155 compound

This is a non-PDB format compatible entry.

Summary for 9BHR

• Entry DOI: 10.2210/pdb9bhr/pdb
• Descriptor: DDB1- and CUL4-associated factor 1, (4P)-N-[(1S)-3-amino-1-(3-chloro-4-fluorophenyl)-3-oxopropyl]-4-(4-chloro-2-fluorophenyl)-5-{(1E)-3-[(2-methoxyethyl)amino]-3-oxoprop-1-en-1-yl}-1H-pyrrole-3-carboxamide (3 entities in total)
• Functional Keywords: wd-repeat, wdr, dcaf1, sgc, structural genomics, psi-2, protein structure initiative, structural genomics consortium, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 72316.68

Authors

kimani, S.,Dong, A.,Li, Y.,Seitova, A.,Al-Awar, R.,Krausser, C.,Wilson, B.,Ackloo, S.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) (deposition date: 2024-04-21, release date: 2024-05-08)

• Primary citation: kimani, S.,Dong, A.,Li, Y.,Seitova, A.,Al-Awar, R.,Krausser, C.,Wilson, B.,Ackloo, S.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.; Crystal structure of the WDR domain of human DCAF1 in complex with OICR-40155 compound; To be published,

Experimental method

X-RAY DIFFRACTION (1.62 Å)