9BEZ

MID domain of human Argo2 bound to RNA

This is a non-PDB format compatible entry.

Summary for 9BEZ

• Entry DOI: 10.2210/pdb9bez/pdb
• Descriptor: Protein argonaute-2, [(3~{S},4~{R},5~{R})-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-4-oxidanyl-oxolan-3-yl] [oxidanyl(phosphonooxy)phosphoryl] hydrogen phosphate (3 entities in total)
• Functional Keywords: mid domain, argonaute2, rna binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 46778.75

Authors

Harp, J.M.,Egli, M. (deposition date: 2024-04-16, release date: 2024-07-10)

• Primary citation: Lei, L.,Harp, J.M.,Chaput, J.C.,Wassarman, K.,Schlegel, M.K.,Manoharan, M.,Egli, M.; Structure and Stability of Ago2 MID-Nucleotide Complexes: All-in-One (Drop) His 6 -SUMO Tag Removal, Nucleotide Binding, and Crystal Growth.; Curr Protoc, 4:e1088-e1088, 2024; PubMed: 38923271; DOI: 10.1002/cpz1.1088

Experimental method

X-RAY DIFFRACTION (1.9 Å)