9B7F

S_SAD structure of HEWL using lossless default compression

9B7F の概要

• エントリーDOI: 10.2210/pdb9b7f/pdb
• 関連するPDBエントリー: 1W6Z 9B7E
• 分子名称: Lysozyme C, 1,2-ETHANEDIOL, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: lossy compression, intensity preservation, structural information retention, s_sad phasing, hydrolase
• 由来する生物種: Gallus gallus (chicken)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14955.02

構造登録者

Jakoncic, J.,Bernstein, H.J.,Soares, A.S.,Horvat, K. (登録日: 2024-03-27, 公開日: 2024-04-10, 最終更新日: 2024-10-16)

主引用文献

Bernstein, H.J.,Jakoncic, J.
Investigation of fast and efficient lossless compression algorithms for macromolecular crystallography experiments.
J.Synchrotron Radiat., 31:647-654, 2024

PubMed Abstract: Structural biology experiments benefit significantly from state-of-the-art synchrotron data collection. One can acquire macromolecular crystallography (MX) diffraction data on large-area photon-counting pixel-array detectors at framing rates exceeding 1000 frames per second, using 200 Gbps network connectivity, or higher when available. In extreme cases this represents a raw data throughput of about 25 GB s, which is nearly impossible to deliver at reasonable cost without compression. Our field has used lossless compression for decades to make such data collection manageable. Many MX beamlines are now fitted with DECTRIS Eiger detectors, all of which are delivered with optimized compression algorithms by default, and they perform well with current framing rates and typical diffraction data. However, better lossless compression algorithms have been developed and are now available to the research community. Here one of the latest and most promising lossless compression algorithms is investigated on a variety of diffraction data like those routinely acquired at state-of-the-art MX beamlines.

PubMed: 38838167
DOI: 10.1107/S160057752400359X

実験手法

X-RAY DIFFRACTION (1.65 Å)