9B56

Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 2

This is a non-PDB format compatible entry.

Summary for 9B56

• Entry DOI: 10.2210/pdb9b56/pdb
• Related: 9B55 9B57 9B58 9B59 9B5A 9B5B
• EMDB information: 44201
• Descriptor: Ubiquitin-conjugating enzyme E2 4, Ubiquitin, E3 ubiquitin-protein ligase pub2, ... (4 entities in total)
• Functional Keywords: ubiquitin, e2, e3, hect, nedd4, rsp5, pub2, ubc4, transthioesterification, thioester, transthiolation, tetrahedral intermediate, adenylation, inhibitor, ligase, nucleus, phosphoprotein, ubl conjugation pathway, ubl, atp atp-binding, amp, nucleotide-binding, isopeptide bond
• Biological source: Schizosaccharomyces pombe 972h-; More
• Total number of polymer chains: 3
• Total formula weight: 70129.23

Authors

Kochanczyk, T.,Lima, C.D. (deposition date: 2024-03-22, release date: 2024-06-05, Last modification date: 2024-09-04)

• Primary citation: Kochanczyk, T.,Hann, Z.S.,Lux, M.C.,Delos Reyes, A.M.V.,Ji, C.,Tan, D.S.,Lima, C.D.; Structural basis for transthiolation intermediates in the ubiquitin pathway.; Nature, 2024; PubMed: 39143218; DOI: 10.1038/s41586-024-07828-9

Experimental method

ELECTRON MICROSCOPY (3.35 Å)