9B2B

Estrogen Receptor Alpha Ligand Binding Domain in Complex with a Complete Estrogen Receptor Antagonists that Favors Tetramer Formation

This is a non-PDB format compatible entry.

Summary for 9B2B

• Entry DOI: 10.2210/pdb9b2b/pdb
• Descriptor: Estrogen receptor, 2-chloro-3-{[{[1-(2-fluorophenyl)cyclopentyl]methyl}(4-{[1-(3-fluoropropyl)azetidin-3-yl]oxy}phenyl)amino]methyl}phenol (3 entities in total)
• Functional Keywords: estrogen receptor, antiestrogen, alpha helical bundle, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 118296.36

Authors

Fink, E.C.,Chawla, R.,Wells, K.S.,Barratt, S.,Myles, D.C.,Pena, G.,Robello, B.W.,Ng, R.,Fanning, S.W. (deposition date: 2024-03-14, release date: 2025-08-27)

• Primary citation: Fanning, S.W.; Estrogen Receptor Alpha Ligand Binding Domain in Complex with a Complete Estrogen Receptor Antagonists that Favors Tetramer Formation; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.08 Å)