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9AYM

Cryo-EM Structure of E.coli produced recombinant N-acetyltransferase 10 (NAT10) in complex with cytidine-acetone-CoA bisubstrate probe

This is a non-PDB format compatible entry.
Summary for 9AYM
Entry DOI10.2210/pdb9aym/pdb
EMDB information43996
DescriptorRNA cytidine acetyltransferase, [[(2~{R},3~{R},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3~{S})-4-[[3-[2-[3-[1-[(2~{R},3~{R},4~{R},5~{S})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-2-oxidanylidene-pyrimidin-4-yl]sulfanyl-2-oxidanylidene-propyl]sulfanylethylamino]-3-oxidanylidene-propyl]amino]-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl] hydrogen phosphate (2 entities in total)
Functional Keywordsrna binding protein, ac4c modification, rna acetyltransferase
Biological sourceChaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
Total number of polymer chains2
Total formula weight245115.52
Authors
Zhou, M.,Marmorstein, R. (deposition date: 2024-03-08, release date: 2024-09-11)
Primary citationZhou, M.,Gamage, S.T.,Tran, K.A.,Bartee, D.,Wei, X.,Yin, B.,Berger, S.,Meier, J.L.,Marmorstein, R.
Molecular Basis for RNA Cytidine Acetylation by NAT10.
Biorxiv, 2024
Cited by
PubMed: 38585770
DOI: 10.1101/2024.03.27.587050
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.29 Å)
Structure validation

225946

数据于2024-10-09公开中

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