9AXP

Crystal Structure of HY11-7E1_Hu3 Fab in Complex with Carfentanil

This is a non-PDB format compatible entry.

Summary for 9AXP

• Entry DOI: 10.2210/pdb9axp/pdb
• Descriptor: HY11-7E1_Hu3 Fab Heavy Chain, HY11-7E1_Hu3 Fab Light Chain, ACETATE ION, ... (5 entities in total)
• Functional Keywords: opioids, mab, carfentanil, cross-reactive, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 4
• Total formula weight: 96429.59

Authors

Rodarte, J.V.,Pancera, M. (deposition date: 2024-03-06, release date: 2024-10-02)

• Primary citation: Rodarte, J.V.,Pravetoni, M.; Structure-based engineering of monoclonal antibodies against fentanyl and carfentanil for improved binding; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)