8ZES

Crystal structure of the Wuhan SARS-CoV-2 RBD (333-541) complexed with P2C5 nanobody

8ZES の概要

• エントリーDOI: 10.2210/pdb8zes/pdb
• 関連するPDBエントリー: 8ZER
• 分子名称: Spike protein S1, Nanobody P2C5, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: sars-cov-2, spike glycoprotein fragment, complex with nanobody, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 206988.53

構造登録者

Sluchanko, N.N.,Varfolomeeva, L.A.,Shcheblyakov, D.V.,Logunov, D.Y.,Gintsburg, A.L.,Popov, V.O.,Boyko, K.M. (登録日: 2024-05-06, 公開日: 2024-09-04)

• 主引用文献: Sluchanko, N.N.,Shcheblyakov, D.V.,Varfolomeeva, L.A.,Favorskaya, I.A.,Dolzhikova, I.V.,Korobkova, A.I.,Alekseeva, I.A.,Esmagambetov, I.B.,Derkaev, A.A.,Prokofiev, V.V.,Zorkov, I.D.,Logunov, D.Y.,Gintsburg, A.L.,Popov, V.O.,Boyko, K.M.; Structural Basis for Evasion of New SARS-CoV-2 Variants from the Potent Virus-Neutralizing Nanobody Targeting the S-Protein Receptor-Binding Domain; Biochemistry Mosc.47, 89:1260-1272, 2024; DOI: 10.1134/S0006297924070083

実験手法

X-RAY DIFFRACTION (3.7 Å)