8Z5J
Beta-catenin Crystal Structure
Summary for 8Z5J
Entry DOI | 10.2210/pdb8z5j/pdb |
Descriptor | Catenin beta-1 (1 entity in total) |
Functional Keywords | beta-catenin, bcl9, structural protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 60187.65 |
Authors | |
Primary citation | Zhu, W.,Liu, C.,Xi, K.,Li, A.,Shen, L.A.,Li, Y.,Jia, M.,He, Y.,Chen, G.,Liu, C.,Chen, Y.,Chen, K.,Sun, F.,Zhang, D.,Duan, C.,Wang, H.,Wang, D.,Zhao, Y.,Meng, X.,Zhu, D. Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting beta-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells. J.Med.Chem., 67:12485-12520, 2024 Cited by PubMed: 38912577DOI: 10.1021/acs.jmedchem.3c02079 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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