8YSA

The co-crystal structure of SARS-CoV-2 Mpro in complex with compound H102

Summary for 8YSA

• Entry DOI: 10.2210/pdb8ysa/pdb
• Descriptor: 3C-like proteinase nsp5, BOC-TBG-PHE-ELL (3 entities in total)
• Functional Keywords: inhibiotr, sars-cov-2, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); More
• Total number of polymer chains: 2
• Total formula weight: 34342.18

Authors

Zheng, W.Y.,Fu, L.F.,Feng, Y.,Han, P.,Qi, J.X. (deposition date: 2024-03-22, release date: 2024-05-08)

• Primary citation: Wang, J.,Sang, X.H.,Zheng, W.Y.,Chan, J.F.,Zhou, J.,Xu, Y.,Fu, L.F.,Feng, Y.,Han, P.,Tsang, J.O.,Yuan, S.F.,An, J.,Yuen, K.Y.,Qi, J.X.,Huang, Z.W.; Discovery, Biological Activity, and Structural Mechanism of a Potent Inhibitor of SARS-CoV-2 Main Protease; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)