8YP3

Crystal structure of UDP-N-acetylglucosamine pyrophosphorylase from Spodoptera frugiperda in complex with UDP-GlcNAc

Summary for 8YP3

Entry DOI	10.2210/pdb8yp3/pdb
Descriptor	UDP-N-acetylglucosamine diphosphorylase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, SULFATE ION, ... (5 entities in total)
Functional Keywords	udp-n-acetylglucosamine pyrophosphorylase, spodoptera frugiperda, udp-glcnac, sugar binding protein
Biological source	Spodoptera frugiperda (fall armyworm)
Total number of polymer chains	4
Total formula weight	220832.15
Authors	Lu, Q.,Liu, T.,Zhou, Y.,Yang, Q. (deposition date: 2024-03-15, release date: 2024-08-07)
Primary citation	Lu, Q.,Zhou, Y.,Ding, Y.,Cui, Y.,Li, W.,Liu, T. Structure and Inhibition of Insect UDP- N -acetylglucosamine Pyrophosphorylase: A Key Enzyme in the Hexosamine Biosynthesis Pathway. J.Agric.Food Chem., 2024 Cited by PubMed: 39039661 DOI: 10.1021/acs.jafc.4c03834 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.12 Å)

Structure validation