8YM2

Crystal structure of AIDA-1 PTB domain in complex with SynGAP NPxF motif

Summary for 8YM2

• Entry DOI: 10.2210/pdb8ym2/pdb
• Descriptor: Ankyrin repeat and sterile alpha motif domain-containing protein 1B, Ras/Rap GTPase-activating protein SynGAP (3 entities in total)
• Functional Keywords: aida-1, anks1b, syngap, ras and rab interactor, ptb domain, protein binding
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 19580.34

Authors

Wang, X.,Wang, Y.,Cai, Q.,Zhang, M. (deposition date: 2024-03-08, release date: 2024-05-29, Last modification date: 2024-06-05)

• Primary citation: Wang, X.,Wang, Y.,Cai, Q.,Zhang, M.; AIDA-1/ANKS1B Binds to the SynGAP Family RasGAPs with High Affinity and Specificity.; J.Mol.Biol., 436:168608-168608, 2024; PubMed: 38759928; DOI: 10.1016/j.jmb.2024.168608

Experimental method

X-RAY DIFFRACTION (2 Å)