8YFX

Cryo EM structure of human phosphate channel XPR1 at inward-facing state

Summary for 8YFX

• Entry DOI: 10.2210/pdb8yfx/pdb
• EMDB information: 39232
• Descriptor: Solute carrier family 53 member 1 (1 entity in total)
• Functional Keywords: phosphate channel, membrane protein, phosphate homeostasis, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 92938.38

Authors

Lu, Y.,Yue, C.,Zhang, L.,Yao, D.,Yu, Y.,Cao, Y. (deposition date: 2024-02-25, release date: 2024-10-09)

• Primary citation: Lu, Y.,Yue, C.X.,Zhang, L.,Yao, D.,Xia, Y.,Zhang, Q.,Zhang, X.,Li, S.,Shen, Y.,Cao, M.,Guo, C.R.,Qin, A.,Zhao, J.,Zhou, L.,Yu, Y.,Cao, Y.; Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1.; Science, :eadp3252-eadp3252, 2024; PubMed: 39325866; DOI: 10.1126/science.adp3252

Experimental method

ELECTRON MICROSCOPY (3.56 Å)