8YE4

The complex of TCR NYN-I and HLA-A24 bound to SARS-CoV-2 Spike448-456 peptide NYNYLYRLF

Summary for 8YE4

• Entry DOI: 10.2210/pdb8ye4/pdb
• Descriptor: MHC class I antigen precusor, Beta-2-microglobulin, Spike protein S1, ... (6 entities in total)
• Functional Keywords: sars-cov-2, tcr-pmhc complex, cd8 t cell epitope, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 184240.36

Authors

Deng, S.S.,Jin, T.C.,Xu, Z.H.,Wang, M.H. (deposition date: 2024-02-21, release date: 2024-08-21)

• Primary citation: Deng, S.,Xu, Z.,Wang, M.,Hu, J.,Liu, Z.,Zhu, F.,Zheng, P.,Kombe Kombe, A.J.,Zhang, H.,Wu, S.,Jin, T.; Structural insights into immune escape at killer T cell epitope by SARS-CoV-2 Spike Y453F variants.; J.Biol.Chem., 300:107563-107563, 2024; PubMed: 39002680; DOI: 10.1016/j.jbc.2024.107563

Experimental method

X-RAY DIFFRACTION (3.2 Å)