8YD9

Crystal structure of p38alpha with an allosteric inhibitor 3

Summary for 8YD9

• Entry DOI: 10.2210/pdb8yd9/pdb
• Related: 7W5O
• Descriptor: Mitogen-activated protein kinase 14, 13-[4-({Imidazo[1,2-a]pyridin-2-yl}methoxy)phenyl]-4,8-dioxa-12,14,16,18-tetraazatetracyclo[9.7.0.0^{3,9}.0^{12,17}]octadeca-1(11),2,9,15,17-pentaen-15-amine, GLYCEROL, ... (4 entities in total)
• Functional Keywords: inhibitor, structural genomics, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 42285.17

Authors

Hasegawa, S.,Kinoshita, T. (deposition date: 2024-02-19, release date: 2025-02-26)

• Primary citation: Kinoshita, T.,Hasegawa, S.; Identification of a novel target site for ATP-independent p38 alpha inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.66 Å)