8YAM

Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound

This is a non-PDB format compatible entry.

Summary for 8YAM

• Entry DOI: 10.2210/pdb8yam/pdb
• Descriptor: RNA (33-MER), 2-[2-(dimethylamino)ethoxy]xanthen-9-one (3 entities in total)
• Functional Keywords: preq1 riboswitch, rna
• Biological source: Caldanaerobacter subterraneus subsp. tengcongensis
• Total number of polymer chains: 1
• Total formula weight: 10507.43

Authors

Numata, T.,Parmar, S.,Schneekloth, J.S. (deposition date: 2024-02-09, release date: 2024-09-11)

• Primary citation: Parmar, S.,Bume, D.D.,Conelly, C.,Boer, R.,Prestwood, P.R.,Wang, Z.,Labuhn, H.,Sinnadurai, K.,Feri, A.,Ouellet, J.,Homan, P.,Numata, T.,Schneekloth Jr., J.S.; Mechanistic Analysis of Riboswitch Ligand Interactions Provides Insights into Pharmacological Control over Gene Expression.; Biorxiv, 2024; PubMed: 38903087; DOI: 10.1101/2024.02.23.581746

Experimental method

X-RAY DIFFRACTION (2.15 Å)