8Y2F

Cryo-EM structure of human dopamine transporter in complex with GBR12909

This is a non-PDB format compatible entry.

Summary for 8Y2F

• Entry DOI: 10.2210/pdb8y2f/pdb
• EMDB information: 38853
• Descriptor: Sodium-dependent dopamine transporter, 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: human dopamine transporter human dopamine transporter, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 62483.49

Authors

Zhao, Y.,Li, Y. (deposition date: 2024-01-25, release date: 2024-08-14)

• Primary citation: Zhao, Y.,Li, Y.; Dopamine reuptake and inhibitory mechanisms in human dopamine transporter; Nature, 2024; DOI: 10.1038/s41586-024-07796-0

Experimental method