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8Y0F

Solution NMR structure of the PTK7-binding DNA aptamer sgc8c

Summary for 8Y0F
Entry DOI10.2210/pdb8y0f/pdb
DescriptorDNA (1 entity in total)
Functional Keywordsdna aptamer, protein tyrosine kinase 7, three-way junction, dna
Biological sourcesynthetic construct
Total number of polymer chains1
Total formula weight12651.13
Authors
He, A.,Wan, L.,Guo, P.,Han, D. (deposition date: 2024-01-22, release date: 2024-06-26)
Primary citationHe, A.,Wan, L.,Zhang, Y.,Yan, Z.,Guo, P.,Han, D.,Tan, W.
Structure-based investigation of a DNA aptamer targeting PTK7 reveals an intricate 3D fold guiding functional optimization
Proc.Natl.Acad.Sci.USA, 2024
Experimental method
SOLUTION NMR
Structure validation

222415

數據於2024-07-10公開中

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