8XSZ
Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNA
This is a non-PDB format compatible entry.
Summary for 8XSZ
Entry DOI | 10.2210/pdb8xsz/pdb |
EMDB information | 38631 |
Descriptor | 28S rRNA, 60S ribosomal protein L7a, 60S ribosomal protein L9, ... (88 entities in total) |
Functional Keywords | ribosome, tigecycline, antibiotic, ccdc124 |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 86 |
Total formula weight | 3982703.42 |
Authors | |
Primary citation | Li, X.,Wang, M.,Denk, T.,Buschauer, R.,Li, Y.,Beckmann, R.,Cheng, J. Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15:5481-5481, 2024 Cited by PubMed: 38942792DOI: 10.1038/s41467-024-49797-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
Download full validation report