8XSE

SARS-CoV-2 RBD + IMCAS-123 + IMCAS-72 Fab

8XSE の概要

• エントリーDOI: 10.2210/pdb8xse/pdb
• EMDBエントリー: 38617
• 分子名称: Spike protein S1, IMCAS-123 H chain, IMCAS-123 L chain, ... (6 entities in total)
• 機能のキーワード: sars-cov-2, broadly neutralizing antibodies, virus, viral protein/immune system, viral protein-immune system complex
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 118404.88

構造登録者

Tong, Z.,Cui, Y.,Xie, Y.,Tong, J.,Gao, G.F.,Qi, J. (登録日: 2024-01-09, 公開日: 2024-07-17)

• 主引用文献: Tong, Z.,Tong, J.,Lei, W.,Xie, Y.,Cui, Y.,Jia, G.,Li, S.,Zhang, Z.,Cheng, Z.,Xing, X.,Ma, H.,Deng, L.,Zhang, R.,Zhao, X.,Liu, K.,Wang, Q.,Qi, J.,Huang, H.,Song, R.,Su, Z.,Wu, G.,Lou, J.,Gao, G.F.; Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1.; Cell Rep, 43:114338-114338, 2024; PubMed: 38850530; DOI: 10.1016/j.celrep.2024.114338

実験手法

ELECTRON MICROSCOPY (2.5 Å)