8XS3

Structure of MPXV B6 and D68 fab complex

Summary for 8XS3

• Entry DOI: 10.2210/pdb8xs3/pdb
• EMDB information: 38613
• Descriptor: D68_heavy chain, D68_light chain, Protein OPG190, ... (5 entities in total)
• Functional Keywords: mpxv antibody, viral protein/immune system, viral protein-immune system complex
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 77556.25

Authors

wu, L.L.,Sun, J.Q. (deposition date: 2024-01-08, release date: 2024-06-12, Last modification date: 2024-06-19)

• Primary citation: Zhao, R.,Wu, L.,Sun, J.,Liu, D.,Han, P.,Gao, Y.,Zhang, Y.,Xu, Y.,Qu, X.,Wang, H.,Chai, Y.,Chen, Z.,Gao, G.F.,Wang, Q.; Two noncompeting human neutralizing antibodies targeting MPXV B6 show protective effects against orthopoxvirus infections.; Nat Commun, 15:4660-4660, 2024; PubMed: 38821921; DOI: 10.1038/s41467-024-48312-2

Experimental method

ELECTRON MICROSCOPY (3.46 Å)