8XQS
Structure of human class T GPCR TAS2R14-DNGi complex with Flufenamic acid.
Summary for 8XQS
Entry DOI | 10.2210/pdb8xqs/pdb |
EMDB information | 38587 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | gpcr, tas2r14, minigsg, flf, bitter receptor, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 232220.84 |
Authors | |
Primary citation | Hu, X.,Ao, W.,Gao, M.,Wu, L.,Pei, Y.,Liu, S.,Wu, Y.,Zhao, F.,Sun, Q.,Liu, J.,Jiang, L.,Wang, X.,Li, Y.,Tan, Q.,Cheng, J.,Yang, F.,Yang, C.,Sun, J.,Hua, T.,Liu, Z.J. Bitter taste TAS2R14 activation by intracellular tastants and cholesterol. Nature, 2024 Cited by PubMed: 38776963DOI: 10.1038/s41586-024-07569-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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