8XQS

Structure of human class T GPCR TAS2R14-DNGi complex with Flufenamic acid.

8XQS の概要

• エントリーDOI: 10.2210/pdb8xqs/pdb
• EMDBエントリー: 38587
• 分子名称: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• 機能のキーワード: gpcr, tas2r14, minigsg, flf, bitter receptor, signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 232220.84

構造登録者

Hu, X.L.,Wu, L.J.,Hua, T.,Liu, Z.J. (登録日: 2024-01-05, 公開日: 2024-07-10)

• 主引用文献: Hu, X.,Ao, W.,Gao, M.,Wu, L.,Pei, Y.,Liu, S.,Wu, Y.,Zhao, F.,Sun, Q.,Liu, J.,Jiang, L.,Wang, X.,Li, Y.,Tan, Q.,Cheng, J.,Yang, F.,Yang, C.,Sun, J.,Hua, T.,Liu, Z.J.; Bitter taste TAS2R14 activation by intracellular tastants and cholesterol.; Nature, 2024; PubMed: 38776963; DOI: 10.1038/s41586-024-07569-9

実験手法

ELECTRON MICROSCOPY (3.3 Å)