8XP8

Crystal structure of d(ACGmCCGT/ACGGCGT) in complex with Echinomycin

Summary for 8XP8

• Entry DOI: 10.2210/pdb8xp8/pdb
• Related PRD ID: PRD_000491
• Descriptor: DNA (5'-D(P*AP*CP*GP*GP*CP*GP*T)-3'), DNA (5'-D(P*AP*CP*GP*(5CM)P*CP*GP*T)-3'), Echinomycin, ... (6 entities in total)
• Functional Keywords: dna-ligand complex, dna, antibiotic, dna-antibiotic complex, dna/antibiotic
• Biological source: Streptomyces echinatus.; More
• Total number of polymer chains: 4
• Total formula weight: 6730.30

Authors

Hou, M.H.,Lin, S.M.,Neidle, H. (deposition date: 2024-01-03, release date: 2024-05-29, Last modification date: 2024-08-28)

• Primary citation: Lin, S.M.,Huang, H.T.,Fang, P.J.,Chang, C.F.,Satange, R.,Chang, C.K.,Chou, S.H.,Neidle, S.,Hou, M.H.; Structural basis of water-mediated cis Watson-Crick/Hoogsteen base-pair formation in non-CpG methylation.; Nucleic Acids Res., 52:8566-8579, 2024; PubMed: 38989613; DOI: 10.1093/nar/gkae594

Experimental method

X-RAY DIFFRACTION (1.64 Å)