8XK6

S2A5 Fab bound to SFTSV glycoprotein Gn

Summary for 8XK6

Entry DOI	10.2210/pdb8xk6/pdb
Descriptor	Envelopment polyprotein, mAb S2A5 Fab heavy chain, mAb S2A5 Fab light chain, ... (4 entities in total)
Functional Keywords	glycoprotein, gn, fab, viral protein
Biological source	Severe fever with thrombocytopenia syndrome virus More
Total number of polymer chains	3
Total formula weight	92220.66
Authors	Deng, Z. (deposition date: 2023-12-22, release date: 2024-07-10, Last modification date: 2024-09-11)
Primary citation	Ren, X.,Sun, J.,Kuang, W.,Yu, F.,Wang, B.,Wang, Y.,Deng, W.,Xu, Z.,Yang, S.,Wang, H.,Hu, Y.,Deng, Z.,Ning, Y.J.,Zhao, H. A broadly protective antibody targeting glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection. Nat Commun, 15:7009-7009, 2024 Cited by PubMed: 39147753 DOI: 10.1038/s41467-024-51108-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.45 Å)

Structure validation