8XIT

Cryo-EM structure of sheep VMAT2 dimer in an atypical fold

Summary for 8XIT

• Entry DOI: 10.2210/pdb8xit/pdb
• EMDB information: 38389
• Descriptor: OaVMAT2-BRIL (1 entity in total)
• Functional Keywords: vesicular monoamine transporter, slc18a2, mfs, apo, conformation, transport protein
• Biological source: Ovis aries
• Total number of polymer chains: 2
• Total formula weight: 137185.38

Authors

Lyu, Y.,Fu, C.,Ma, H.,Sun, Z.,Su, Z.,Zhou, X. (deposition date: 2023-12-20, release date: 2024-08-14)

• Primary citation: Lyu, Y.,Fu, C.,Ma, H.,Su, Z.,Sun, Z.,Zhou, X.; Engineering of a mammalian VMAT2 for cryo-EM analysis results in non-canonical protein folding.; Nat Commun, 15:6511-6511, 2024; PubMed: 39095428; DOI: 10.1038/s41467-024-50934-5

Experimental method

ELECTRON MICROSCOPY (3.2 Å)