8XCC

Cryo-EM structure of Cas12o1 (E100K), crRNA and target DNA complex

Summary for 8XCC

Entry DOI	10.2210/pdb8xcc/pdb
EMDB information	38239
Descriptor	Cas12j19(E100K), CrRNA, TS-DNA, ... (4 entities in total)
Functional Keywords	crispr-cas protein, rna binding protein-rna-dna complex, rna binding protein/rna/dna
Biological source	unclassified sequences More
Total number of polymer chains	4
Total formula weight	151901.06
Authors	Zhang, X. (deposition date: 2023-12-08, release date: 2024-12-11, Last modification date: 2025-08-20)
Primary citation	Duan, Z.,Zhang, X.,Zhang, J.T.,Ji, X.,Liu, R.,Chen, Y.,Li, S.,Jia, N.,Gao, H.,Xin, Y.,Jia, N.,Zhu, J.K. Structure and genome editing activity of the novel CRISPR-Cas12o1 effector. Cell Res., 35:145-148, 2025 Cited by PubMed: 39516663 DOI: 10.1038/s41422-024-01050-y PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation