8XB3

Structural mechanism of substrate binding and inhibition of the human Norepinephrine Transporter

Summary for 8XB3

• Entry DOI: 10.2210/pdb8xb3/pdb
• EMDB information: 38209
• Descriptor: GFP-MBP-solute carrier family 6 member 2, 1-[(3-iodanylphenyl)methyl]guanidine, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: meta-iodobenzylguanidine, radafaxin, neuroendocrine tumors, antidepression, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 1
• Total formula weight: 139193.31

Authors

Ji, W.M.,Wu, J.X. (deposition date: 2023-12-05, release date: 2024-06-26)

• Primary citation: Wu, J.X.,Ji, W.M.,Liu, J.M.; Structural mechanism of substrate binding and inhibition of the human Norepinephrine Transporter; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.8 Å)