8X8X

Crystal structure of ROCK2 with GNS-2591 inhibitor

Summary for 8X8X

• Entry DOI: 10.2210/pdb8x8x/pdb
• Descriptor: Rho-associated protein kinase 2, ~{N}-methyl-3-[[1-oxidanylidene-6-[5-(trifluoromethyl)-1~{H}-pyrazol-4-yl]isoquinolin-2-yl]methyl]benzamide, SULFATE ION, ... (4 entities in total)
• Functional Keywords: inhibitor, transferase, transferase-inhibitor complex, transferase/inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 91101.40

Authors

Park, T.H.,Bong, S.M.,Lee, S.J.,Lee, B.I. (deposition date: 2023-11-29, release date: 2024-12-04)

• Primary citation: Park, T.H.,Lee, B.I.; crystal structure of rock2 with GNS-2591 inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)