8X7I
Cryo-EM structures of RNF168/UbcH5c-Ub in complex with H2AK13Ub nucleosomes determined by intein-based E2-Ub-NCP conjugation strategy
Summary for 8X7I
Entry DOI | 10.2210/pdb8x7i/pdb |
EMDB information | 38099 |
Descriptor | Histone H3.2, Ubiquitin, ZINC ION, ... (11 entities in total) |
Functional Keywords | rnf168, nucleosome, h2ak13/15 ubiquitination, nuclear protein, nuclear protein-dna complex, nuclear protein/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 13 |
Total formula weight | 216262.02 |
Authors | Ai, H.S.,Tong, Z.B.,Deng, Z.H.,Pan, M.,Liu, L. (deposition date: 2023-11-24, release date: 2024-08-07) |
Primary citation | Ai, H.,Tong, Z.,Deng, Z.,Shi, Q.,Tao, S.,Liang, J.,Sun, M.,Wu, X.,Zheng, Q.,Liang, L.,Li, J.B.,Gao, S.,Tian, C.,Liu, L.,Pan, M. Capturing Snapshots of Nucleosomal H2A K13/K15 Ubiquitination Mediated by the Monomeric E3 Ligase RNF168 Biorxiv, 2024 Cited by DOI: 10.1101/2024.01.02.573964PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.27 Å) |
Structure validation
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