8X5E

Cryo-EM structure of human XPR1 in open state

Summary for 8X5E

• Entry DOI: 10.2210/pdb8x5e/pdb
• EMDB information: 38067
• Descriptor: Solute carrier family 53 member 1, PHOSPHATE ION, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate (3 entities in total)
• Functional Keywords: transport open state, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 59329.34

Authors

Jiang, D.H.,Yan, R. (deposition date: 2023-11-17, release date: 2024-07-03, Last modification date: 2024-08-28)

• Primary citation: Yan, R.,Chen, H.W.,Liu, C.Y.,Zhao, J.,Wu, D.,Jiang, J.Q.,Gong, J.K.,Jiang, D.H.; Human XPR1 structures reveal phosphate export mechanism; Nature, 2024; DOI: 10.1038/s41586-024-07852-9

Experimental method

ELECTRON MICROSCOPY (3.61 Å)