8X1Z
HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y:DNA:E-CFCP-TP ternary complex
Summary for 8X1Z
Entry DOI | 10.2210/pdb8x1z/pdb |
Descriptor | HIV-1 reverse transcriptase p66 subunit, HIV-1 RT p51 subunit, DNA/RNA (38-MER), ... (7 entities in total) |
Functional Keywords | reverse transcriptase, hiv-1, hbv, drug resistance, nucleoside analogue, e-cfcp, transferase |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 6 |
Total formula weight | 256868.39 |
Authors | |
Primary citation | Yasutake, Y.,Hattori, S.I.,Kumamoto, H.,Tamura, N.,Maeda, K.,Mitsuya, H. Deviated binding of anti-HBV nucleoside analog E-CFCP-TP to the reverse transcriptase active site attenuates the effect of drug-resistant mutations. Sci Rep, 14:15742-15742, 2024 Cited by PubMed: 38977798DOI: 10.1038/s41598-024-66505-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.62 Å) |
Structure validation
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