8WZ0

SARS-CoV-2 3CLpro bound to covalent inhibitor

8WZ0 の概要

• エントリーDOI: 10.2210/pdb8wz0/pdb
• 分子名称: 3C-like proteinase nsp5, (2~{R})-~{N}-[4,4-bis(fluoranyl)cyclohexyl]-2-[(2-chloranyl-2-fluoranyl-ethanoyl)-[4-(trifluoromethyloxy)phenyl]amino]-2-pyrimidin-5-yl-propanamide (3 entities in total)
• 機能のキーワード: protease inhibitor, covalent, virus, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 68728.84

構造登録者

Peng, J.,Sun, D.,Ding, X. (登録日: 2023-11-01, 公開日: 2025-05-07)

• 主引用文献: Peng, J.,Sun, D.,Ding, X.; SARS-CoV-2 3CLpro bound to covalent inhibitor; To Be Published,

実験手法

X-RAY DIFFRACTION (2.45 Å)