8WTY
Cryo-EM structure of noradrenaline transporter in complex with ziprasidone
Summary for 8WTY
| Entry DOI | 10.2210/pdb8wty/pdb |
| EMDB information | 37846 |
| Descriptor | Sodium-dependent noradrenaline transporter, 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloranyl-1,3-dihydroindol-2-one (2 entities in total) |
| Functional Keywords | noradrenaline transporter, ziprasidone, structural protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 64214.04 |
| Authors | |
| Primary citation | Hu, T.,Yu, Z.,Zhao, J.,Meng, Y.,Salomon, K.,Bai, Q.,Wei, Y.,Zhang, J.,Xu, S.,Dai, Q.,Yu, R.,Yang, B.,Loland, C.J.,Zhao, Y. Transport and inhibition mechanisms of the human noradrenaline transporter. Nature, 2024 Cited by DOI: 10.1038/s41586-024-07638-zPDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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