8WS3

Crystal structure of SARS-CoV-2 Main Protease (Mpro) with covalent inhibitor 5,8-Dihydroxy-1,4-naphthoquinone

Summary for 8WS3

• Entry DOI: 10.2210/pdb8ws3/pdb
• Descriptor: 3C-like proteinase nsp5, DI(HYDROXYETHYL)ETHER, 5,8-bis(oxidanyl)naphthalene-1,4-dione, ... (5 entities in total)
• Functional Keywords: covid-19 main protease, covalent inhibitor, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV,SARS-CoV-2)
• Total number of polymer chains: 2
• Total formula weight: 68131.62

Authors

Yang, Y.,Wu, D. (deposition date: 2023-10-16, release date: 2024-10-23)

• Primary citation: Yang, Y.,Wu, D.; Covalent inhibitors of SARS-CoV-2 main protease; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)