8WOX

Cryo-EM structure of SARS-CoV-2 prototype RBD in complex with rabbit ACE2 (local refinement)

8WOX の概要

• エントリーDOI: 10.2210/pdb8wox/pdb
• EMDBエントリー: 37701
• 分子名称: Spike protein S1, Angiotensin-converting enzyme, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: sars-cov-2 omicron, receptor-binding domains (rbds), rabbit, angiotensin-converting enzyme 2 (ace2), viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 95255.25

構造登録者

Li, L.J.,Shi, K.Y.,Yu, G.H.,Gao, G.F. (登録日: 2023-10-08, 公開日: 2023-12-13, 最終更新日: 2024-02-28)

• 主引用文献: Shi, K.,Li, L.,Luo, C.,Xu, Z.,Huang, B.,Ma, S.,Liu, K.,Yu, G.,Gao, G.F.; Structural basis of increased binding affinities of spikes from SARS-CoV-2 Omicron variants to rabbit and hare ACE2s reveals the expanding host tendency.; Mbio, 15:e0298823-e0298823, 2024; PubMed: 38112468; DOI: 10.1128/mbio.02988-23

実験手法

ELECTRON MICROSCOPY (2.75 Å)