8WH6

MPOX E5 hexamer ADP and ssDNA bound and clear primase domain conformation

Summary for 8WH6

• Entry DOI: 10.2210/pdb8wh6/pdb
• EMDB information: 37530
• Descriptor: Uncoating factor OPG117, DNA (5'-D(P*CP*CP*C)-3'), ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: monkey pox, helicase, dna replication, complex, viral protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Monkeypox virus; More
• Total number of polymer chains: 7
• Total formula weight: 545520.27

Authors

Zhang, Z.,Dong, C. (deposition date: 2023-09-22, release date: 2024-09-25)

• Primary citation: Xu, Y.,Wu, Y.,Zhang, Y.,Gao, K.,Wu, X.,Yang, Y.,Li, D.,Yang, B.,Zhang, Z.,Dong, C.; Essential and multifunctional mpox virus E5 helicase-primase in double and single hexamer.; Sci Adv, 10:eadl1150-eadl1150, 2024; PubMed: 39167653; DOI: 10.1126/sciadv.adl1150

Experimental method

ELECTRON MICROSCOPY (3.27 Å)